Aug 9, 2018 · in this study, we show that fenbendazole (fz) exhibits a moderate microtubule depolymerizing activity towards human cancer cells, but possesses a potent antitumor effect. To ensure patient safety in the repurposing use of fenbendazole, it is crucial to perform clinical trials to assess its potential anticancer effects, optimal doses, therapeutic regimen, and. Fenbendazole (fbz) has been safely used as an antiparasitic agent in animals for decades, and the anticancer effects of fbz have been studied through various mechanisms. 1) fenbendazole acts as a moderate microtubule destabilizing agent and causes cancer cell death by modulating multiple cellular pathways. 2) unexpected antitumorigenic effect of.
Currently, no clinical trials directly examine the potential of fenbendazole in cancer therapy. A youtube video of a us patient diagnosed with small cell lung cancer claimed he had been cured by fenbendazole (animal anthelmintic), while attending a clinical trial with other anti.
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